Transcutaneous Peripheral Nerve Stimulation for Essential Tremor

Is an artificial intelligence (AI)–driven TPNS device superior to a sham device in reducing essential tremor?In this randomized clinical trial that included 125 adults with essential tremor, use of the TPNS device reduced the modified Activities of Daily Living score of the Essential Tremor Rating Assessment Scale by a clinically meaningful 6.9 points at 90 days, significantly more than the 2.7-point reduction seen in the sham-treated group.The TPNS device improved activities related to upper limb tremor at 90 days and could be an effective noninvasive treatment for essential tremor.

Corresponding Author: William G. Ondo, MD, Houston Methodist Hospital, 6560 Fannin, Ste 802, Houston, TX 77030 (wondo@houstonmethodist.org).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.