Atopic Dermatitis and Markers of Early Cardiovascular Risk in Children and Adolescents

Is more active and severe atopic dermatitis (AD) throughout childhood associated with early cardiovascular risk factors?In this cohort study including 9281 participants, there were no associations between AD and most cardiovascular risk factors, no consistent evidence for a dose response by AD severity, and no associations between trajectories of more active and severe AD with measures of subclinical atherosclerosis and cardiometabolic risk.Findings indicating that children with AD did not have early signs of increased cardiovascular risk suggest that standardized screening of all children with AD is unlikely to improve identification of those in need of early intervention.

Corresponding Author: Katrina Abuabara, MA, MD, MSCE, Department of Dermatology, University of California, San Francisco, 2340 Sutter St, N421, San Francisco, CA 94115 (Katrina.abuabara@ucsf.edu).

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