Original Investigation

Neighborhood Disadvantage and Access to Liver Transplant Referral for Severe Alcohol-Associated Hepatitis

JAMA Network Open 10.1001/jamanetworkopen.2026.2567

March 19, 2026 at 11:00 AM EDT

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Is neighborhood disadvantage associated with referral for liver transplant in patients with severe alcohol-associated hepatitis?In this cohort study of 325 patients, neighborhood disadvantage was associated with referral at intermediate Model for End-Stage Liver Disease scores.The findings of this study suggest that outreach strategies informed by social context may improve access to liver transplant and may be applicable across organ systems, as referral is a critical equity leverage point.

Corresponding Author: Lauren D. Nephew, MD, MSCE, Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, 107 S Indiana Ave, Indianapolis, IN 47405 (lnephew@iu.edu).

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