Immune-Enhancing Nutrition and Outcomes After Radical Cystectomy

Among patients undergoing radical cystectomy for bladder cancer, does perioperative specialized immunonutrition reduce 30-day postoperative complications compared with standard isocaloric nutrition?In this randomized clinical trial of 178 evaluable adults undergoing radical cystectomy, 62.2% of patients receiving immunonutrition and 58.0% receiving standard isocaloric nutrition experienced at least one 30-day complication. This difference was not statistically significant.This trial found that perioperative immunonutrition did not reduce 30-day postoperative complications compared with standard oral nutrition support.

Corresponding Author: Jill M. Hamilton-Reeves, PhD, RD, CSO, Department of Urology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160 (jhamilton-reeves@kumc.edu).

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