Adjunctive Psychosocial Interventions and Opioid Abstinence Among Patients Receiving Buprenorphine

What is the comparative effectiveness of 2 psychosocial treatments—cognitive-behavioral therapy (CBT) and peer recovery support (PRS)—on opioid abstinence when used as adjunctive therapy to office-based buprenorphine treatment in adults with opioid use disorder (OUD)?This randomized clinical trial of 340 adults with OUD taking buprenorphine found that neither PRS, CBT, nor a combination of these psychosocial interventions yielded differential effects on opioid abstinence.These results suggest that adjunctive psychosocial interventions may not enhance buprenorphine treatment outcomes in the early stages of treatment.

Corresponding Author: Michelle R. Lent, PhD, Philadelphia College of Osteopathic Medicine, 4190 City Ave, Rowland Hall, Philadelphia, PA 19131 (MichelleLe@pcom.edu).

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