Shiga Toxin–Producing Outbreak in Canadian Daycare Centers

What were the health care resource utilization and clinical outcomes associated with a large single-source pediatric Shiga toxin–producing (STEC) outbreak, beginning in Canadian daycare centers?In this cohort study, 326 primary and 33 secondary infections were identified among 288 children and 71 adults; among the 285 children with available outcome data, there were 508 and 395 emergency department and STEC clinic visits, respectively. Overall, 40 children were hospitalized, 21 children developed hemolytic uremic syndrome (HUS), and 9 children required dialysis; daily laboratory monitoring identified all future HUS cases.This cohort study found that significant health care resources were used to monitor, treat, and optimize outcomes in this large single-source STEC outbreak.

Corresponding Author: Mohamed Eltorki, MBChB, MSc, Alberta Children’s Hospital, 28 Oki Dr NW, Room C4-638, Calgary, AB T3B 6A8, Canada (mmeltork@ucalgary.ca).

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