Factors Associated With Thromboembolism in Neonates

What are the factors associated with neonatal venous thrombosis?In this systematic review and meta-analysis of 60 studies including 3 366 507 neonates, preeclampsia, low birth weight, neonatal infection, and cardiac disease were associated with venous thrombosis in neonates. Several putative factors were analyzed in fewer than 3 studies, and their impact could not be explored.These findings suggest that preeclampsia, low birth weight, cardiac disease, and infection may be risk factors for neonatal venous thrombosis, although limited data regarding common conditions and medications persist, highlighting the need for further studies and risk stratification.

Corresponding Author: Marie-Claude Pelland-Marcotte, MD, PhD, Department of Pediatrics, Centre Hospitalier Universitaire de Québec, 2705, Blvd Laurier, Quebec City, Quebec G1V 4G2, Canada (marie-claude.pelland-marcotte.1@ulaval.ca).

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