Original Investigation

Geographic and Temporal Differences in Sickle Cell Disease Hospitalizations in New York State

JAMA Network Open 10.1001/jamanetworkopen.2026.10045

May 01, 2026 at 11:00 AM EDT

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What were the geographic and temporal patterns of sickle cell disease (SCD) hospitalizations in New York State from 2009 to 2022?In this cross-sectional study of 42 271 SCD hospitalizations in New York State, New York City accounted for the largest proportion of admissions, Central New York and the Hudson Valley had the longest mean hospital stays, and Long Island had the highest mean total charges. The proportions of hospitalizations classified as major severity and major risk of mortality increased over time, with the highest levels observed in 2022.These findings suggest the need for region-specific strategies to improve access to specialized care and reduce severe outcomes.

Corresponding Author: Chukwuemeka Iloegbu, MSc, New York University School of Global Public Health, 708 Broadway, New York, NY 10003 (iloegc01@nyu.edu).

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