Clinical Pharmacists, Medications, and Contingency Management for Targeting Smoking in HIV Clinics

What are optimal clinical pharmacist–delivered treatment strategies for promoting cigarette smoking reduction among people with HIV?In this randomized clinical trial involving 323 participants, those receiving nicotine replacement therapy (NRT) with or without contingency management (CM) had similar reductions in cigarettes per day (CPD) at 12 weeks. Among participants who started with NRT alone and did not achieve week 12 abstinence, adding CM led to lower CPD than switching to oral medications. Participants who started with NRT and then added CM achieved lowest CPD at week 24.Study findings, indicating that CM is an effective adjunct to clinical pharmacist–delivered NRT for improving tobacco-related outcomes, provide HIV clinics with guidance on strategies for addressing cigarette smoking reduction among people with HIV.

Corresponding Author: E. Jennifer Edelman, MD, MHS, Yale School of Medicine, 367 Cedar St, ESH A, New Haven, CT 06510 (ejennifer.edelman@yale.edu).

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