Original Investigation

Anxiety, Depression, and Care Barriers in Adults With Intellectual and Developmental Disabilities

JAMA Network Open 10.1001/jamanetworkopen.2025.60205

February 20, 2026 at 11:00 AM EST

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Are anxiety, depression, and barriers to mental health care more prevalent among adults with intellectual and developmental disabilities (IDDs) than those without functional limitations?In this cross-sectional study of 44 478 US adults from the 2021, 2022, and 2023 National Health Interview Surveys, adults with IDDs had a higher prevalence of diagnosed anxiety and depression, more frequent and severe symptoms, greater psychiatric medication use, and more cost-related barriers to counseling or therapy than adults without functional limitations.These findings suggest that adults with IDDs experience significant mental health disparities and barriers to care, indicating a need for disability-informed mental health services and policies.

Corresponding Author: Dimitri Christakis, MD, MPH, Center for Child Health, Behavior, and Development, Seattle Children’s Research Institute, 1920 Terry Ave, Seattle WA 98101 (dchristakis@specialolympics.org).

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