Medications for Alcohol Use Disorder Among Patients With Severe Alcohol-Related Liver Disease

Is the use of medications for alcohol use disorder (MAUDs) associated with lower long-term mortality among patients with severe alcohol-related liver disease (ALD)?In this cohort study of 1309 adults undergoing liver transplant evaluation, use of MAUDs for at least 3 months was associated with a significant survival benefit, with 6.6% higher 1-year survival and 18.5% higher 3-year survival.This study suggests that, among patients with alcohol use disorder, pharmacotherapy should be considered, even for patients with severe ALD.

Corresponding Author: Akshay Shetty, MD, Department of Medicine, University of California, Los Angeles, UCLA Medical Center, 100 Medical Plaza, Ste 700, Los Angeles, CA 90095 (akshayshetty@mednet.ucla.edu).

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