Cerebral Oximetry–Guided Treatment and Cerebral Oxygenation in Extremely Preterm Infants

Does treatment guided by cerebral oximetry using a near-infrared spectroscopy device from a single manufacturer and a neonatal sensor improve cerebral oxygenation stability in extremely preterm infants?In this randomized clinical trial of 100 infants born at less than 29 weeks’ gestation, the burden of cerebral hypoxia and hyperoxia was significantly lower in the intervention group compared with the standard care group.In this study, treatment guided by cerebral oximetry improved the stability of cerebral oxygenation in extremely preterm infants.

Corresponding Author: Dr Pranav R. Jani, PhD, Department of Neonatology, Westmead Hospital, Westmead, NSW 2145 Australia (pranav.jani@health.nsw.gov.au).

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