Original Investigation

Counseling and Cardiovascular Disease Risk Factor Control in Long-Term Cancer Survivors

JAMA Network Open 10.1001/jamanetworkopen.2025.55863

February 05, 2026 at 11:00 AM EST

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Among adult survivors of childhood cancer with undertreated hypertension, dyslipidemia, or glucose intolerance, can remotely delivered, clinician-led, self-management counseling sessions reduce undertreatment more than provision of screening results alone?In a randomized clinical trial of 347 participants, there was no significant difference after 1 year between the study groups: 26% of intervention participants and 30% of enhanced usual care control participants had less undertreatment of cardiovascular disease risk factors.In this study, self-management counseling did not reduce cardiovascular risk factor undertreatment beyond simply providing hypertension, lipid level, and diabetes screening results to high-risk cancer survivors and their primary care clinicians.

Corresponding Author: Eric J. Chow, MD, MPH, Fred Hutchinson Cancer Center, 1100 Fairview Ave N, PO Box 19024, Mailstop M4-C308, Seattle, WA 98109 (ericchow@uw.edu).

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