Modeled Health and Economic Burden of Frailty and Falls Among Adults With HIV

What are the anticipated lifetime health losses and costs attributable to frailty and falls among people with HIV (PWH) and viral suppression in the United States?In this decision analytic model with results scaled to an estimated population size of 521 994 PWH, there would be a projected 214 000 quality-adjusted life-years (QALYs) lost and $5.0 billion in lifetime costs attributable to prefrailty among PWH. There would be a projected 1 091 000 QALYs lost and $8.8 billion attributable to frailty and a projected 141 000 QALYs lost and $3.4 billion attributable to falls.The findings of this study suggest that the anticipated clinical and economic burden of frailty and falls among aging PWH in the United States could be substantial.

Corresponding Author: Karen C. Smith, PhD, Department of Orthopedic Surgery, Brigham and Women’s Hospital, 60 Fenwood Rd, Ste 5016, Boston, MA 02115 (ksmith81@bwh.harvard.edu).

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