Health-Related Quality of Life and Long-Term Survival After Cardiac Arrest
JAMA Network Open 10.1001/jamanetworkopen.2025.52832January 07, 2026 at 11:00 AM EST
Is health-related quality of life (HRQOL) 3 to 6 months after cardiac arrest associated with long-term survival?In this cohort study including 2000 survivors of in-hospital cardiac arrest and 1108 survivors of out-of-hospital cardiac arrest (OHCA), poorer HRQOL reported with the EuroQoL 5-dimension 5-level (EQ-5D-5L) tool questionnaire was associated with reduced long-term survival (assessed up to 7 years) in both cohorts, although uncertainty was higher among OHCA survivors.Findings suggest that HRQOL measured after cardiac arrest with the EQ-5D-5L may help identify survivors at risk of reduced long-term survival and inform follow-up care and rehabilitation; further research should confirm clinical utility.
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