Original Investigation

Gender Identity Milestones and Hormone Utilization in Transgender Men and Women in China

JAMA Network Open 10.1001/jamanetworkopen.2025.52440

January 06, 2026 at 11:00 AM EST

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What are the characteristics of gender identity development and gender-affirming hormone therapy (GAHT) utilization among Chinese transgender men and women?This cross-sectional study of 1462 transgender men and 2834 transgender women found that while transgender men began gender identity explorations earlier, transgender women progressed faster toward medical affirmation. Although access to qualified GAHT services has improved in China, challenges persist in medical accessibility and social acceptance.These findings emphasize the need for early, individualized care for transgender youths and underscore the importance of expanding accessible and patient-centered transgender health care services in China.

Corresponding Author: Ye Liu, MD, Department of Endocrinology and Metabolism, State Key Laboratory of Female Fertility Promotion, Peking University Third Hospital, No. 49 North Garden Rd, Haidian District, 100191, Beijing, China (yeliumed@bjmu.edu.cn).

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