Research Letter

Use of Ursodeoxycholic Acid and Cancer Risk for Patients With Primary Biliary Cholangitis

JAMA Network Open 10.1001/jamanetworkopen.2025.50907

December 19, 2025 at 11:00 AM EST

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This cohort study uses electronic health record data to compare cancer incidence among adults with primary biliary cholangitis who were or were not treated with ursodeoxycholic acid (UDCA).

Corresponding Author: Xiang Shu, PhD, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 633 Third Ave, New York, NY 10017 (shux@mskcc.org).

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