Original Investigation

Residential Neighborhood Disadvantage and Access to Kidney Transplantation

JAMA Network Open 10.1001/jamanetworkopen.2025.49679

December 30, 2025 at 11:00 AM EST

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Does residing in a high-disadvantage neighborhood affect access to waitlisting and kidney transplantation (KT)?This cohort study found that for adults with end-stage kidney disease, residence in high-disadvantage neighborhoods was associated with a significantly lower likelihood of waitlisting, any KT, live-donor KT, and preemptive KT. The associations between neighborhood disadvantage and KT access were most pronounced among minoritized patients and those residing in the Western regions of the US, and residence in suburban or rural high-disadvantage neighborhoods was associated with especially low access to live-donor KT.The findings suggest that residence in high-disadvantage neighborhoods is associated with reduced access to waitlisting and KT and contributes to persistent racial and ethnic disparities in access to live-donor KT and preemptive KT.

Corresponding Author: Mara A. McAdams-DeMarco, PhD, Department of Surgery, New York University Grossman School of Medicine, One Park Ave, Sixth Floor, New York, NY 10016 (mara.mcadamsdemarco@nyulangone.org).

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