Original Investigation

Next-Day HIV Viral Load Test Result and Linkage to Care Among Persons Living With or at Risk of HIV

JAMA Network Open 10.1001/jamanetworkopen.2025.48380

December 16, 2025 at 11:00 AM EST

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Does providing a next-day HIV viral load (VL) test result increase linkage-to-care (LTC) rates among people with HIV or with risk factors for HIV acquisition?In this randomized clinical trial that included 195 adults, there was no difference overall in LTC among adults who did (intervention) or did not (control) receive an HIV VL test result.Provision of an HIV VL test result did not improve LTC in persons with or at risk of HIV infection.

Corresponding Author: Matthew M. Hamill, MBChB, PhD, Division of Infectious Diseases, Johns Hopkins School of Medicine, 5200 Eastern Ave, Mason F. Lord Center Tower, Ste 373, Baltimore, MD 21224 (mhamill6@jhu.edu).

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