Original Investigation

Transient and Long-Term Risks of Common Physical Activities in People With Low Back Pain

JAMA Network Open 10.1001/jamanetworkopen.2025.47915

December 09, 2025 at 11:00 AM EST

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Are physical activities associated with transient risks (≤24 hours) of low back pain (LBP) flares and long-term disability?This case-crossover study nested within a cohort study of 416 adults with LBP found that, of 10 common activities, greater time spent in lifting, bending, pushing or pulling, twisting, and squatting was significantly associated with greater risks of LBP flares; sitting was significantly associated with lower risk of LBP flares. No activity was significantly associated with LBP-related disability at 1-year follow-up.This study’s results suggest that although some activities were associated with transient risks of a subsequent LBP flare, none were associated with long-term disability.

Corresponding Author: Pradeep Suri, MD, MSc, VA Puget Sound Health Care System, 1660 S Columbian Way, Seattle, WA 98018 (pradeep.suri@va.gov).

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