Vitamin D Levels During Pregnancy and Dental Caries in Offspring

Are maternal vitamin D levels associated with early dental caries (ECCs) in offspring, and is there variation by pregnancy trimester?In this cohort study of 4109 mother-offspring pairs, lower levels of maternal 25-hydroxyvitamin D during pregnancy, particularly in the mid- to late-trimesters, were associated with increased odds of ECCs.These findings suggest that integrating vitamin D screening and supplementation into routine prenatal care during and even before pregnancy may help reduce the odds of childhood ECC.

Corresponding Author: Yunxian Yu, MD, PhD, Department of Public Health, and Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China (yunxianyu@zju.edu.cn).

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