Antenatal Corticosteroids and Bronchopulmonary Dysplasia in Very Preterm Infants

Is there an association between antenatal corticosteroids (ACS) and bronchopulmonary dysplasia (BPD) in very preterm infants?In this cohort study of 1097 infants with gestational age less than 30 weeks, a complete course of ACS was significantly associated with a reduced risk of BPD, particularly in singleton infants delivered vaginally at 28 weeks’ to 28 weeks 6 days’ gestation.These findings suggest that ACS could optimize pulmonary outcomes and reduce incidence of BPD in very preterm infants.

Corresponding Authors: Xin-Zhu Lin, BM (xinzhufj@163.com), and Wei Shen, MD (shenweibest@163.com), Departments of Neonatology and Pediatrics, Women and Children’s Hospital, School of Medicine, Xiamen University, Xiamen, Fujian, 361000, China.

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