Original Investigation

Triazole Resistance and Misidentification of in Southern California

JAMA Network Open 10.1001/jamanetworkopen.2025.43630

December 04, 2025 at 11:00 AM EST

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What are the true species identities of infections in Southern California, and how common is triazole resistance among them?In this cross-sectional study that tested 1505 clinical isolates, 664 were identified as using standard microbiological methods; however, DNA sequencing revealed that 73.8% were actually . This species showed reduced susceptibility to itraconazole and posaconazole relative to other species. is a prevalent but largely unrecognized cause of triazole-resistant infections in Southern California.

Corresponding Author: Lance B. Price, PhD, Department of Environmental and Occupational Health, Co-director, Antibiotic Resistance Action Center, The George Washington University, 800 22nd Street NW, Seventh Floor, Office 7590, Washington, DC 20052 (lprice@gwu.edu).

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