Information-Theoretic Trigger Surprisal and Future Headache Activity

Is there an association between information-theoretic trigger surprisal and future headache activity?In this cohort study including 109 participants, total surprisal score was associated with future migraine risk at 12 hours and 24 hours.The findings of this study underscore the value of a person-centered, information-theoretic approach to understanding migraine triggers, one that moves beyond static lists of potential causes to account for the unpredictable and context-sensitive nature of daily life.

Corresponding Author: Dana P. Turner, MSPH, PhD Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Boston, MA 02114 (dpturner@mgh.harvard.edu).

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