Original Investigation

Cost-Effectiveness of Linkage Case Management for Hospitalized People With HIV

JAMA Network Open 10.1001/jamanetworkopen.2025.42105

November 05, 2025 at 11:00 AM EST

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Is a case management intervention to improve HIV care engagement cost-effective compared with enhanced standard care from Tanzanian Ministry of Health and societal perspectives?In this economic evaluation including 500 patients, Daraja, a linkage case management intervention administered by social workers, was more costly than enhanced standard care from both stakeholder perspectives but was associated with improvements in disability-adjusted life-years. At 12 months, Daraja’s likelihood of cost-effectiveness was approximately 0.75 across a wide range of willingness-to-pay thresholds.The Daraja intervention had a high probability of being regarded as cost-effective according to various cost-effectiveness threshold estimates.

Corresponding Author: Sean M. Murphy, MA, PhD, Department of Population Health Sciences, Weill Cornell Medicine, 575 Lexington Ave, New York, NY 10022 (smm2010@med.cornell.edu).

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