Brief Digital Interventions for Psychological Distress
JAMA Network Open 10.1001/jamanetworkopen.2025.40502October 31, 2025 at 11:00 AM EDT
Which brief digital intervention most effectively reduces mild, moderate, and severe levels of psychological distress among college students?This artificial intelligence–enhanced response-adaptive randomized clinical trial involving 1282 distressed college students found that smartphone-based physical activity and mindfulness were most effective for severe distress and that physical activity and sleep hygiene were most effective for mild distress; no significant differences were observed for moderate distress. The trial’s novel methods improved efficiency by reducing control group allocation.These findings support using brief smartphone-based physical activity for mild and severe distress, mindfulness for severe distress, and sleep hygiene for mild distress.
Link to the article in your story
We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)
Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Need more information? Contact us.