Research Letter

Arterial Spin Labeled MRI to Detect Early Placental Perfusion Differences in Fetal Heart Disease

JAMA Network Open 10.1001/jamanetworkopen.2025.37282

October 13, 2025 at 11:00 AM EDT

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This cohort study evaluates the use of arterial spin labeling magnetic resonance imaging (ASL MRI) to quantify placental perfusion in pregnant individuals with a fetus with congenital heart disease.

Corresponding Authors: Rachel L. Leon, MD, PhD, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Cary Building, F3.122K, Dallas, TX 75390-9063 (rachel.leon@utsouthwestern.edu); Durga Udayakumar, PhD, Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905 (udayakumar.durga@mayo.edu).

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