Breast Cancer Incidence Rates in Ghanaian and US Black Women From 2013 Through 2015

Do age-standardized incidence rates of estrogen receptor (ER)-negative and ER-positive breast tumors in Ghana support a possible increased susceptibility to ER-negative breast cancer in women of West African ancestry?This cross-sectional study including 1071 women in Ghana and 121 548 women in the US with breast cancer from 2013 through 2015 found that age-standardized incidence rates of ER-negative tumors were similar for Ghanaian and US non-Hispanic Black women. ER-positive tumors were lower for women from Ghana compared with non-Hispanic Black women.Findings from this study of the similarity between Ghanaian and US non-Hispanic Black women for age-standardized incidence rates of ER-negative but not ER-positive breast tumors suggest that there may be shared etiologic factors associated with ER-negative breast cancer that need identification.

Corresponding Authors: Brittny C. Davis Lynn, PhD, MPH (brittny.davislynn@nih.gov), and Jonine D. Figueroa, PhD, MPH (jonine.figueroa@nih.gov& Genetics, National Cancer Institute, 9609 Medical Center Dr, Rockville, MD 20892.

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