All-Cause and Cause-Specific Mortality Among Patients With Narcolepsy
JAMA Network Open 10.1001/jamanetworkopen.2025.36771October 09, 2025 at 11:00 AM EDT
Is narcolepsy associated with an increased risk of all-cause and cause-specific mortality?In this cohort study of 3187 patients with narcolepsy, neither all-cause nor cause-specific (natural, unnatural, accidental, or suicide) mortality was elevated compared with 12 748 sex- and age-matched controls or 3287 siblings without narcolepsy.These findings suggest there is no association between narcolepsy and mortality; however, the findings warrant replication in diverse settings with continued clinical surveillance.
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