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IL-1 Receptor Antagonist Antibodies in Idiopathic Recurrent Pericarditis

JAMA Network Open 10.1001/jamanetworkopen.2025.36691

October 09, 2025 at 11:00 AM EDT

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This cohort study investigates the prevalence and role of autoantibodies targeting the endogenous interleukin 1 (IL-1) receptor antagonist in patients with recurrent pericarditis with an inflammatory phenotype.

Corresponding Author: Maddalena Alessandra Wu, MD, Division of Internal Medicine, ASST Fatebenefratelli Sacco, Department of Biomedical and Clinical Sciences, University of Milan, Via G. B. Grassi 74, 20157 Milan, Italy (wu.maddalena@asst-fbf-sacco.it).

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