Interaction Between Immigration, Physical Activity, Mental Health, and All-Cause Mortality Among US Adults

Are interactions between immigrant status, physical activity, and serious psychological distress (SPD) associated with all-cause mortality?This cohort study of 587 931 US adults from 1998 to 2019 found a significant interaction among immigration, physical activity, and SPD status. Immigrants with SPD who engaged in physical activity had a lower all-cause mortality risk compared with immigrants with SPD who lacked physical activity, as well as nonimmigrants who lacked physical activity regardless of SPD status or nonimmigrants who engaged in physical activity with SPD.These findings suggest that interventions considering interactions among immigration, physical activity, and SPD status may be factors associated with reducing mortality risks.

Corresponding Author: David Adzrago, PhD, Division of Intramural Research, National Institute on Minority Health and Health Disparities, National Institutes of Health, 11545 Rockville Pike, Rockville, MA 20818 (david.adzrago@nih.gov).

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