Allostatic Load and Racial and Rural Disparities in Breast Cancer Survival

Does allostatic load help explain racial and rural disparities in breast cancer survival?In this cohort study of 3069 patients with stage I to III breast cancer, higher allostatic load was associated with an increased risk of mortality. Decomposition analyses suggested that the contribution of allostatic load to racial and rural disparities in survival was not statistically significant.This study found that allostatic load was associated with worse breast cancer survival, highlighting the need for interventions that address chronic stress and promote health equity.

Corresponding Authors: Jie Shen, PhD, Department of Public Health Sciences, School of Medicine, University of Virginia, 560 Ray C. Hunt Drive, Charlottesville, VA 22903 (cua9zd@virginia.edu); Hua Zhao, PhD, Department of Public Health Sciences, School of Medicine, University of Virginia, 560 Ray C. Hunt Drive, Charlottesville, VA 22903 (qqx7mw@virginia.edu).

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