Original Investigation

Differential Use of Depression and Anxiety Medications in Adults With a History of Cancer

JAMA Network Open 10.1001/jamanetworkopen.2025.27585

August 19, 2025 at 11:00 AM EDT

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Are sociodemographic characteristics associated with antidepressant and anxiolytic use in cancer survivors?In this cross-sectional study using national data that included 5091 adult cancer survivors, non-Hispanic Black respondents had decreased odds of antidepressant use and anxiolytic use compared with non-Hispanic White cancer survivors, a significant difference. There were also significant differences by cancer type.While this study found that cancer survivors were more likely to use medication for depression and anxiety, disparities by race and ethnicity still existed in the use of these medications.

Corresponding Author: Nosayaba Osazuwa-Peters, BDS, PhD, MPH, CHES, Department of Head and Neck Surgery and Communication Sciences, Duke University School of Medicine, 40 Duke Medicine Circle, Duke South Orange Zone 4212, DUMC 3805, Durham, NC 27710-4000 (nosa.peters@duke.edu).

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