Original Investigation

Neurologic Medication Costs in a Direct-to-Consumer Pharmacy vs Commercial Insurance Plans

JAMA Network Open 10.1001/jamanetworkopen.2025.27476

August 19, 2025 at 11:00 AM EDT

Read the full article

What is the difference in neurologic medication costs between a direct-to-consumer pharmacy and commercial insurance plans?In this cross-sectional study of 33 medications available for purchase through a direct-to-consumer pharmacy, the direct-to-consumer pharmacy out-of-pocket costs were 75% higher and total costs were 413% lower than commercial pharmacies for neurologic medications.These results suggest that a direct-to-consumer pharmacy has the potential to reduce total prescription drug medication costs and offers similar out-of-pocket costs for uninsured patients to conventional pharmacies in commercial insurance plans.

Corresponding Author: James F. Burke, MD, Department of Neurology, Division of Health Services Research, Wexner Medical Center, The Ohio State University, 410 W 10th Ave, Columbus, OH 43210 (james.burke@osumc.edu).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2025.27476?utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_term=081925

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks