Original Investigation

Differences in the Cancer Burden and Current Funding of NCI-Designated Cancer Centers

JAMA Network Open 10.1001/jamanetworkopen.2025.24564

August 01, 2025 at 11:00 AM EDT

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Is there an association between Cancer Center Support Grant (CCSG) funding of National Cancer Institute (NCI)-Designated Cancer Centers and the cancer burden of their catchment areas?This population-based cross-sectional study found no association between CCSG funding and catchment area cancer incidence or mortality rates. Funding was positively associated with catchment area percentages of rural population and persons living with a disability and negatively associated with the percentage of population belonging to a racial or ethnic minority group.These findings suggest that CCSG funding of NCI-Designated Cancer Centers does not currently align well with the distribution of cancer-related needs across catchment areas.

Corresponding Author: Todd Burus, MA, MAS, University of Kentucky, 760 Press Ave, Ste 460, Lexington, KY 40508 (tburus@uky.edu).

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