Prevalence of Orthostatic Autonomic Dysregulation in Pediatric Concussion
JAMA Network Open 10.1001/jamanetworkopen.2025.22309July 22, 2025 at 11:00 AM EDT
What is the prevalence and clinical presentation of autonomic dysregulation (AD), characterized by orthostatic hypotension, tachycardia, and symptom provocation, within 45 days of a pediatric concussion?In this cohort study using medical record review of 451 pediatric patients diagnosed with concussion, 9.98% showed physiological evidence of AD and 23.15% reported symptom provocation during postural change. Physiological AD was not always accompanied by subjective symptom reporting.This study challenges existing clinical assumptions about pediatric concussion management and reinforces the need for objective physiological testing in concussion assessment.
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