Research Letter

GLP-1 RA Use and Survival Among Older Adults With Cancer and Type 2 Diabetes

JAMA Network Open 10.1001/jamanetworkopen.2025.21887

July 18, 2025 at 11:00 AM EDT

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This cohort study evaluates whether older adults with type 2 diabetes and cancer have improved survival when taking glucagon-like peptide-1 receptor agonists (GLP-1RAs) compared with sodium-glucose cotransporter-2 inhibitors and dipeptidyl peptidase-4 inhibitors.

Corresponding Author: Jingchuan Guo, MD, PhD, Department of Pharmaceutical Outcomes and Policy, University of Florida College of Pharmacy, 1889 Museum Rd, DSIT 6004, Gainesville, FL 32606 (guoj1@ufl.edu).

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