Fasting Duration and Differences Across Routine Laboratory Tests
JAMA Internal Medicine 10.1001/jamainternmed.2026.4718September 28, 2026 at 11:00 AM EDT
This cross-sectional study found that fasting duration was associated with differences exceeding analytical performance specifications for only a few analytes, mainly glucose, triglycerides, γ-glutamyl transferase, and lipase. No estimable within-person difference between the 8- to 12-hour and more than 12-hour groups exceeded an available APS. These findings support analyte-specific rather than uniform fasting requirements.
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