Hypertensive Disorders of Pregnancy Subtypes and Long-Term Cardiovascular Risk

Do risks and patterns of cardiovascular events differ across hypertensive disorder of pregnancy (HDP) subtypes?In this cohort study of 570 843 women, HDPs were associated with increased cardiovascular risk, with 2.10 additional cardiovascular events per 1000 person-years over a median of 6.5 years; among subtypes, superimposed preeclampsia was associated with the highest risk. All subtypes were associated with increased risk of heart failure and stroke and most with cardiovascular death, whereas associations for myocardial infarction and atrial fibrillation varied across subtypes.These findings suggest that HDP subtypes are associated with heterogeneous long-term cardiovascular risks, underscoring the need for tailored postpartum surveillance strategies.

Corresponding Authors: Kyungdo Han, PhD, Department of Statistics and Actuarial Science, Soongsil University, 369 Sangdo-ro, Dongjak-gu, Seoul 06978, Republic of Korea (hkd917@naver.com); Jun-Bean Park, MD, PhD, Department of Internal Medicine, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea (nanumy1@gmail.com).

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