Invited Commentary

Evidence for Clinical Treatment Decisions Without Randomized Data

JAMA Internal Medicine 10.1001/jamainternmed.2025.6579

December 08, 2025 at 11:00 AM EST

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Corresponding Author: Jason H. Wasfy, MD, MPhil, Heart and Vascular Institute, Mass General Brigham, Harvard Medical School, 55 Fruit St, GRB 8-843, Boston, MA 02114 (jwasfy@mgh.harvard.edu).

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