Prior Authorization and Associated Delays and Denials of Branded Medication Dispensation
JAMA Health Forum 10.1001/jamahealthforum.2026.0760April 17, 2026 at 11:00 AM EDT
For branded medication prescriptions that are initially rejected by the prior authorization (PA) review, how many are eventually approved and how much time does the process require?In this cross-sectional study of 205 896 medication dispensations initially rejected, 35% were processed in 1 day and 54% were eventually approved. Prescriptions with multiple PA reviews, additional rejection reasons, and refills were delayed and patients with Medicaid coverage or multiple disease conditions experienced fewer prescription approvals.When filling a branded medication that was initially rejected by PA, most patients experienced treatment delays and/or eventual denials, outcomes that were associated with claim adjudication complexity, prescription type, and patient characteristics.
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