Original Investigation

Prescription Drug Monitoring Program Reminder Emails, Program Use, and Prescribing

JAMA Health Forum 10.1001/jamahealthforum.2025.5623

December 19, 2025 at 11:00 AM EST

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Can reminder emails to clinicians increase Prescription Drug Monitoring Program (PDMP) use and encourage safer prescribing of opioids and other controlled substances?In this randomized clinical trial including 7872 clinicians, reminder emails significantly raised PDMP engagement, including account creation, database searches, and searches for patients with a history of risky prescribing. The effects persisted for at least 7 months and were approximately twice as large for emails that focused on the legal requirements mandating use of the PDMP rather than on its clinical benefits; prescribing quality and volume remained unchanged.Email communications provide a low-cost, scalable approach to quickly increase PDMP use and assist clinicians seeking to prescribe medications safely, but the impact of reminder emails may not translate into large-scale changes in prescribing practices.

Corresponding Author: Adam Sacarny, PhD, Department of Health Policy and Management, Mailman School of Public Health, Columbia University, 722 W 168 St, 4th Floor, New York, NY 10032 (ajs2102@columbia.edu).

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