Global Disparities in Premature Mortality
JAMA Health Forum 10.1001/jamahealthforum.2025.3479October 03, 2025 at 11:00 AM EDT
How does the probability of premature death (PPD)—defined as probability of dying before 70 years of age—in 7 global regions and the 30 most populous countries compare to a frontier representing the lowest country-level PPD?In this cross-sectional study, the frontier PPD fell from 57% to 12% from 1900 to 2019. Of the 7 global regions highlighted here, the greatest convergence toward the frontier since 2000 was observed in sub-Saharan Africa, which had the same PPD as the frontier almost 150 years earlier in the year 2000 and just over 100 years earlier in 2019.This study underscores persistent inequality in living standards and access to health-enhancing technologies, as well as context-specific obstacles that can impact long-run declines in PPD.
Link to the article in your story
We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)
Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
Need more information? Contact us.