Digital Intradermal Hyaluronidase Injections for Sclerodactyly in Systemic Sclerosis

This case report describes off-label intradermal hyaluronidase injections as a targeted antifibrotic treatment for a woman in her 50s with systemic sclerosis–related sclerodactyly.

Corresponding Author: Kimberly Hashemi, MD, Department of Dermatology, The Medical University of South Carolina, 135 Rutledge Ave, MSC 578, Charleston, SC 29425 (bowerman@musc.edu).

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