Observation

GLP-1 Receptor Agonist Therapy in Patients With Extragenital Lichen Sclerosus

JAMA Dermatology 10.1001/jamadermatol.2026.0476

April 29, 2026 at 11:00 AM EDT

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This case report describes 2 patients with lichen sclerosus whose symptoms improved with glucagon-like peptide-1 receptor agonists.

Corresponding Author: Neda Shahriari, MD, Department of Dermatology, Brigham and Women’s Hospital, Harvard Medical School, 221 Longwood Ave, Boston, MA 02115 (nshahriari@bwh.harvard.edu).

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