Patient Values and Preferences in Chronic Urticaria Treatment

What factors do patients and caregivers value and prefer when choosing treatments for chronic urticaria (CU)?This systematic review of 18 studies involving 28 497 participants found that patients with CU prioritized rapid symptom improvement (within 2 weeks) and sustained control of hives, itch, and/or swelling. When considering treatments of similar effectiveness, patients preferred those with milder adverse effects (eg, kidney impairment, injection site reactions), less administration burden—oral or topical rather than injection or infusion—and more rapid onset.These systematically synthesized CU-specific values and preferences can be used to improve CU management and clinical practice guidelines.

Corresponding Author: Derek K. Chu, MD, PhD, Department of Medicine and Department of Health Research Methods, McMaster University Medical Centre, 1280 Main St W, Room 3H30, Hamilton, ON L8S 4K1, Canada (chudk@mcmaster.ca).

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