Observation

Treatment of Porokeratosis Ptychotropica With Upadacitinib

JAMA Dermatology 10.1001/jamadermatol.2025.3519

October 01, 2025 at 11:00 AM EDT

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This case report describes a patient with refractory porokeratosis ptychotropica who experienced substantial improvement in symptoms with upadacitinib treatment.

Corresponding Author: Jian-Bo Wang, MD, Department of Dermatology, Henan Provincial People’s Hospital, People’s Hospital of Zhengzhou University, People’s Hospital of Henan University, Zhengzhou 450003, Henan, China (wangjianbo1020@163.com).

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