Upadacitinib for Treatment of Hyper-IgE Syndrome

This case report describes a young man with a heterozygous variation in who was diagnosed with hyper-IgE syndrome and whose condition improved with upadacitinib therapy.

Corresponding Authors: Hong Liu, PhD (hongyue2519@hotmail.com), and Furen Zhang, PhD (zhangfuren@hotmail.com), Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences, 27397 Jingshi Rd, Jinan 250022, Shandong, China.

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