Original Investigation

Seven-Year Valve Durability With Transcatheter or Surgical Aortic Valve Replacement

JAMA Cardiology 10.1001/jamacardio.2026.2299

June 24, 2026 at 10:15 AM EDT

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Are long-term outcomes following transcatheter aortic valve replacement (TAVR) similar to those following surgery?In this ad hoc analysis of the PARTNER 3 randomized clinical trial, the incidence rates at 7-year follow-up of structural valve dysfunction, bioprosthetic valve failure, and valve reintervention were low and similar for TAVR vs surgery.In low-risk patients with symptomatic severe aortic stenosis randomized to TAVR or surgery, 7-year follow-up showed similar valve durability between groups; these findings may inform discussions of valve replacement strategies.

Corresponding Author: Philippe Pibarot, DVM, PhD, Institut Universitaire de Cardiologie et de Pneumologie de Québec, 2725 Chemin Sainte-Foy, Québec, QC G1V-4G5, Canada (philippe.pibarot@med.ulaval.ca).

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