Review

A Contemporary Look at the Landscape of Treatment of Tricuspid Regurgitation

JAMA Cardiology 10.1001/jamacardio.2025.4337

November 26, 2025 at 11:00 AM EST

Read the full article

The effective management of tricuspid regurgitation necessitates a multidisciplinary approach, integrating input from interventional cardiology, cardiac surgery, heart failure cardiology, imaging, and electrophysiology. Surgical and transcatheter interventions such as tricuspid transcatheter-edge-to-edge repair and transcatheter tricuspid valve replacement have demonstrated favorable early clinical and functional outcomes, but ongoing research is necessary to refine patient selection and improve treatment decision-making. Individualizing treatment plans to optimize health outcomes and quality of life for patients with tricuspid regurgitation is paramount.

Corresponding Authors: Kent C. Y. So, MBChB, Division of Cardiology, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Clinical Sciences Building, Shatin, NT, 9/F, Hong Kong SAR, China (kentso987@gmail.com); Gilbert H. L. Tang, MD, MSc, MBA, Department of Cardiovascular Surgery and Medicine, Mount Sinai Health System, 1190 Fifth Ave, GP2W, Box 1028, New York, NY 10029 (gilbert.tang@mountsinai.org).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

https://jamanetwork.com/journals/jamacardiology/fullarticle/10.1001/jamacardio.2025.4337?utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_term=112625

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.

Editor's Picks